Candida albicans the chameleon: transitions and interactions between multiple phenotypic states confer phenotypic plasticity
نویسندگان
چکیده
منابع مشابه
Regulation of phenotypic transitions in the fungal pathogen Candida albicans
The human commensal fungus Candida albicans can cause not only superficial infections, but also life-threatening disease in immunocompromised individuals. C. albicans can grow in several morphological forms. The ability to switch between different phenotypic forms has been thought to contribute to its virulence. The yeast-filamentous growth transition and white-opaque switching represent two ty...
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Phenotypic diversity is critical to the lifestyles of many microbial species, enabling rapid responses to changes in environmental conditions. In the human fungal pathogen Candida albicans, cells exhibit heritable switching between two phenotypic states, white and opaque, which yield differences in mating, filamentous growth, and interactions with immune cells in vitro. Here, we address the in ...
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Candida albicans is the most frequent opportunistic fungal agent in human being. One of its virulence factors is phenotypic switching. In this study, we investigated the susceptibility of different phenotypes of C. albicans, obtained from clinical specimens, to fluconazole (FLZ) and voriconazole (VRZ) with microdilution reference method. In this study, 281 C. albicans of six different phenotype...
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ژورنال
عنوان ژورنال: Current Opinion in Microbiology
سال: 2015
ISSN: 1369-5274
DOI: 10.1016/j.mib.2015.06.016